FI-LAB

5 papers8 findings

Human studies report FI-LAB prediction of mortality in emergency department patients and critically ill acute ischaemic stroke patients at a 24-hour landmark. A preprint reports improved mortality discrimination within MIMIC-IV, while a review describes prediction of 12-month mortality after endovascular therapy for acute ischaemic stroke.

Humans4

Effects

Mortality discrimination

upin humans1

1 study

FI-LAB improves mortality discrimination in humans (+0.0132 AUC (95% CI 0.0081 to 0.0184)).
Humansinternally in MIMIC-IV patients
Added prognostic value of a laboratory frailty index for hospital mortality in surgical intensive care: a two-database cohort study
Research Square16 Sep 2026Preprint

Associations

Mortality

upin humans2HR 2.04

2 studies

FI-LAB predicts mortality in humans (AUC 0.774 to 0.808).
Humanscritically ill acute ischemic stroke patients at 24-h landmarkn = 1,296
Baseline and 72-h dynamic laboratory deficit burden for mortality through day 90 after acute ischemic stroke in critical care: landmark analyses with temporal validation
Frontiers in neurology3 Sep 2026
FI-LAB predicts mortality in humans (HR 2.04, 95% CI 1.99–2.09).
Humansin emergency department patients (MIMIC-IV-ED)
Evaluation of the FI-Lab, a laboratory-based, automated frailty index for acute care: A multicohort study
PLoS medicine1 Sep 2026

12-month mortality

upin humans1HR 3.61

1 study

FI-LAB predicts 12-month mortality in humans (adjusted HR 3.61, 95% CI 1.98-6.61).
Reviewafter endovascular therapy for acute ischaemic stroke
Frailty as a Predictor of Clinical Outcomes After Acute Ischemic Stroke in Older Adults: A Systematic Review and Meta-Analysis
Cureus19 Aug 2026

Malignant arrhythmia

upin humans1

1 study

FI-LAB raises the risk of malignant arrhythmia in humans (SHR = 2.68, 95% CI: 1.39-5.18).
Humanscritically ill patients with coronary artery disease (severe frailty vs mild frailty)
Association between frailty and clinical outcomes in critically ill coronary artery disease patients: A retrospective cohort study
Science progress11 Aug 2026