EV-augmented CA-125 model

1. EV-augmented CA-125 model predicts high-grade serous ovarian cancer in humans (AUROC 0.97; sensitivity 99% (95% CI 89–100); specificity 85% (95% CI 68–91)).

   “For distinguishing HGSOC from non-cancers, an EV-augmented CA-125 model achieved an AUROC of 0.97 in plasma and 0.96 in serum”

   Humansdistinguishing HGSOC from non-cancersplasma

   Immunoaffinity-enriched extracellular vesicle proteomics for high-grade serous ovarian cancer - A UKOPS nested case-control analysis

   Gynecologic oncology·Oct 15, 2026

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