Epigenetically captured skin aging acceleration

1. Sun exposure is associated with epigenetically captured skin aging acceleration in humans.

   “capture environmentally induced acceleration in sun-exposed skin alongside lifestyle and topical treatment–associated variation.”

   Humanssun-exposed skinskin

   Skin DNA Methylation Encodes Multidimensional Facial Aging Phenotypes with Distinct Biological Architectures

   bioRxiv (Cold Spring Harbor Laboratory)·16 Mar 2026Preprint

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