Epigenetic clock replicate deviation

1. Principal-component epigenetic clock method decreases epigenetic clock replicate deviation in silico (within 1.5 years).

   “retrained principal-component versions of six clocks show agreement between most replicates within 1.5 years”

   In silico

   A computational solution for bolstering reliability of epigenetic clocks: Implications for clinical trials and longitudinal tracking

   Nature aging·15 Jul 2022

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