ELM-RPE thickness

Older age is associated with ELM-RPE thickness in humans.

“Older adults, regardless of sex, showed ELM-RPE contraction limited to the fovea and parafovea compared with younger adults.”

HumansLight-adapted participants without overt ophthalmologic diseasefovea and parafovean = 25

Macular Metabolism in Young and Older Adults: A Preliminary Optical Coherence Tomography Biomarker Study

Investigative ophthalmology & visual science·1 Jul 2026