DNA methylation biomarker

Biomarker2 papers2 findings

Humans1
In silico1

Interventions

2

Gas mask

downin humans1Low certainty

1 study

Gas mask decreases DNA methylation biomarker in humans.
HumansTiO2 exposed workersplasma
Detection of cancer epigenetic alterations in a pilot cohort of workers exposed to TiO₂ · Frontiers in toxicology · 22 Sep 2026

Titanium dioxide

upin humans1Low certainty

1 study

Titanium dioxide increases DNA methylation biomarker in humans.
Humansoccupational exposure in TiO2 pigment powder production workerspigment powderplasma
Detection of cancer epigenetic alterations in a pilot cohort of workers exposed to TiO₂ · Frontiers in toxicology · 22 Sep 2026

Titanium dioxide →

Funding

UKRI | Medical Research Council£1.4m1 grant since 2026

Blood- and saliva-based DNA methylation biomarkers of disease
UKRI | Medical Research CouncilUniversity of Edinburgh£1.4m2026–2030

Latest

5

Frontiers in ToxicologyHumansYesterday

Detection of cancer epigenetic alterations in a pilot cohort of workers exposed to TiO₂

Molecular Biology ReportsReview11 Sep

DNA methylation biomarkers for early detection of ovarian cancer

Nature Human BehaviourHuman trial9 Sep

Effects of a randomized controlled trial of unconditional cash transfers on epigenetic measures of ageing and cognition in children and mothers

Nature MedicineIn silico22 Aug

Responsiveness of epigenetic aging biomarkers to longevity interventions in humans

AAIC 2025 AbstractHumans24 Dec

DNA methylation‐wide association study of prevalent and incident dementia in the US Health and Retirement Study

ADA Scientific Sessions 2025 AbstractHuman trial13 Jun

DNA Methylation Biomarkers Associated with Weight Loss Response for Individuals with Prediabetes Based on Korean Diabetes Prevention Study (KDPS)