De novo copy number variations

1. Radiation increases de novo copy number variations in mice.

   “the number of the mice with de novo copy number variations (specifically, deletions) was significantly increased in the offspring of C57BL/6J male mice exposed to 20 mGy/day gamma-rays for 400 days”

   Animalspaternal exposure to 20 mGy/day gamma-rays for 400 days (total dose: 8000 mGy) in male mice20 mGy/day (total dose: 8000 mGy)400 days

   Increased Frequency of Copy Number Variations Revealed by Array Comparative Genomic Hybridization in the Offspring of Male Mice Exposed to Low Dose-Rate Ionizing Radiation

   International journal of molecular sciences·18 Nov 2021

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