Aging Cell
A signal from aging skin fat delays hair growth in mice
Experiments in male mice aged 18–24 months linked a protein from skin fat to immune cell buildup and delayed entry into the hair-growth phase.Experiments in male mice aged 18–24 months linked a protein from skin fat to immune cell buildup and delayed entry into the hair-growth phase.
Mouse studySkin
Who was studiedYoung male C57BL/6 mice, 14 consecutive days, against PBS-injected mice
What changedHair growth started later in mice injected with MCP-1 than in control mice
The catchFat-cell origin rests on overlapping stains; macrophages also expressed MCP-1