Cytoplasmic pH

There is 1 paper on cytoplasmic pH in aging research: none in people yet, 1 in cells.

Biomarker

1 paper studies it2 findings

See all 1 papers on cytoplasmic pH

  • Cells1

Interventions

1

Rapamycin

downin yeast cells1

1 study
  1. Rapamycin decreases cytoplasmic pH in yeast cells (TORC1 inhibition by rapamycin treatment or TOR1 deletion).

    “Inhibition of TORC1 signaling by either TOR1 deletion or rapamycin treatment decreased PMA1 expression, pHc, and vacuolar pH”

    CellsTORC1 inhibition by rapamycin treatment or TOR1 deletion

    TORC1 signaling regulates cytoplasmic pH through Sir2 in yeast

    Aging cell

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Upstream

1

GTR1

upin yeast cells1

1 study
  1. GTR1 increases cytoplasmic pH in yeast cells (expression of constitutively active GTR1Q65L).

    “activation of TORC1 signaling by expressing constitutively active GTR1 (GTR1Q65L) resulted in the opposite phenotypes”

    Cellsexpression of constitutively active GTR1Q65L

    TORC1 signaling regulates cytoplasmic pH through Sir2 in yeast

    Aging cell

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