Cumulative deficit frailty

Biomarker

1 paper2 findings

  • Humans1

Associations

2

Alzheimer's disease brain signature

downin humans1

1 study
  1. Cumulative deficit frailty is associated with Alzheimer's disease brain signature in humans (r = -0.16, p = .005).

    “between CDF and AD brain signature (r = -0.16, p = .005) after controlling for chronological age, smoking, race/ethnicity, and education.”

    Humansmales

    Association of cumulative deficit frailty with brain age and Alzheimer's disease-related brain structure starting in late-middle age

    The journals of gerontology. Series A, Biological sciences and medical sciences23 Dec 2025

More on Alzheimer's disease brain signature

Brain-predicted age difference

upin humans1

1 study
  1. Cumulative deficit frailty is associated with brain-predicted age difference in humans (r = 0.36, p < .001).

    “significant covariance between random intercepts for CDF and brain-predicted age difference (r = 0.36, p < .001)”

    Humansmales

    Association of cumulative deficit frailty with brain age and Alzheimer's disease-related brain structure starting in late-middle age

    The journals of gerontology. Series A, Biological sciences and medical sciences23 Dec 2025

More on Brain-predicted age difference

Latest

Nov 2025: 0Dec 2025: 2Jan 2026: 0Feb 2026: 0Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 1Sep 2026: 0Oct 2026: 04 in 12 months