CTX-1/P1NP ratio

Biomarker

1 paper1 finding

  • Animals1

Interventions

1

HM17321

downin mice1

1 study
  1. HM17321 decreases CTX-1/P1NP ratio in mice (0.11 vs. 0.20 vehicle).

    “HM17321 significantly decreased serum CTX-1/P1NP ratio (0.11 vs. 0.20, vehicle; 0.14, Sham vehicle) suggesting a shift toward a more balanced bone remodeling.”

    Animalsin HFD/OVX mice8 weeks

    Protective Effects of HM17321, a Novel UCN2 Analog, on Obesity-Associated Musculoskeletal Diseases in Mouse Models

    ADA Scientific Sessions 2026 abstract5 Jun 2026

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