CPH-Lung

Biomarker

1 paper2 findings

  • Humans1

Effects

1

Lung cancer prediction sensitivity

upin humans1

1 study
  1. CPH-Lung increases lung cancer prediction sensitivity in humans (57.6% versus 39.2%; P < .0001).

    “sensitivities were 57.6% versus 39.2% in women (P < .0001)”

    HumansEver-smokers; comparison with PLCOm2012 at 77.7% specificity6 yearsfemales

    Model using blood tests better predicts lung cancer risk

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology12 Oct 2026

Associations

1

6-year lung cancer risk

upin humans1

1 study
  1. CPH-Lung predicts 6-year lung cancer risk in humans (AUC 0.783 (95% CI 0.731–0.835) versus 0.720 (95% CI 0.669–0.770); P = .0059).

    “the CPH-Lung versus the PLCOm2012 yielded AUCs of 0.783 (95% CI, 0.731 to 0.835) versus 0.720 (95% CI, 0.669 to 0.770)”

    HumansEver-smokers in CCHS; comparison with PLCOm20126 yearsn = 3,195

    Model using blood tests better predicts lung cancer risk

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology12 Oct 2026

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Journal of Clinical Oncology

Model using blood tests better predicts lung cancer risk

In 3,195 Danish people who had smoked, a score measuring predictive performance was 0.783 for the model versus 0.720 for an established model.In 3,195 Danish people who had smoked, a score measuring predictive performance was 0.783 for the model versus 0.720 for an established model.

Cohort study of 3,195 peopleLung cancer