Cortical TSPO binding

Age increases cortical TSPO binding in mice (+15%, P < 0.001).

“cortical TSPO binding increased to a maximum at 14.5 mo (+15%, P < 0.001) and remained high to 20 mo”

Animalscortex

Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·13 Jul 2017