Cortical thickness differences between high and low cognitive performers

Age is associated with cortical thickness differences between high and low cognitive performers in humans.

“the differences in cortical thickness between high vs. low cognitive performance groups diminished with increasing age.”

HumansCross-sectional comparison across age groupscerebral cortex

Structural Brain Indicators of Cognitive Performance in Middle and Late Adulthood: The Human Connectome Project in Aging/Aging Adult Brain Connectome Cohort

bioRxiv (Cold Spring Harbor Laboratory)·22 Jan 2026Preprint