Cortical microglial gene expression

1. Microglial repopulation is associated with cortical microglial gene expression in mice.

   “Repopulated cortical microglia in aged, but not young, mice exhibited aberrant gene expression patterns”

   Animalsfollowing PLX3397 withdrawal in C57BL/6J micecortical microgliamales

   Aging Converts Microglial Repopulation into Maladaptive Reprogramming that Exacerbates Cognitive Deficits

   bioRxiv (Cold Spring Harbor Laboratory)·Jan 9, 2026Preprint

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