Corpus callosum fractional anisotropy

1. Corpus callosum fractional anisotropy predicts dementia in humans (AUC = 0.970).

   “The model demonstrated strong discrimination between dementia and age-matched controls (area under the receiver operating characteristic curve [AUC] = 0.970; sensitivity = 90.9%; specificity = 93.2%).”

   Humanscross-validation model discrimination

   Corpus callosum fractional anisotropy from routine diffusion tensor imaging predicts dementia in older adults beyond clinical risk factors

   GeroScience·8 Aug 2026

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