Confidence-interval width ratio relative to random validation
Biomarker1 paper1 finding
- In silico1
Interventions
1APOE4-balanced validation
downin silico1Very low certainty
1 study
APOE4-balanced validation
downin silico1Very low certainty
APOE4-balanced validation decreases confidence-interval width ratio relative to random validation in silico (0.923).
In silicoat PET budget 200 for Centiloid >= 24 PET positivity APOE4 contrast
Spending Scarce Confirmatory PET Measurements: Target-Aligned Validation in A4/LEARN · arXiv · 23 Aug 2026 · Preprint