CLI Frailty Index

There is 1 paper on CLI Frailty Index in aging research: 1 observational study in people.

Biomarker

1 paper studies it4 findings

See all 1

“The CLI Frailty Index is a risk factor for 2-year AFS in CLI patients after revascularization.”
Influence of frailty on treatment outcomes after revascularization in patients with critical limb ischemiaJournal of vascular surgery2017doi:10.1016/j.jvs.2017.04.048
  • Humans1

Effects

1

Prognostic discrimination

upin humans1

1 study
  1. CLI Frailty Index is linked with better prognostic discrimination in humans (compared with the modified Frailty Index in critical limb ischemia after revascularization) (AUC 0.72 versus 0.63; P = .01).

    “The CLI Frailty Index area under the curve was 0.72 compared with 0.63 for the modified Frailty Index (P = .01).”

    Humanscompared with the modified Frailty Index in critical limb ischemia after revascularizationn = 266

    Influence of frailty on treatment outcomes after revascularization in patients with critical limb ischemia

    Journal of vascular surgery

Associations

3

30-day or hospital mortality

upin humans1HR 6.32

1 study
  1. CLI Frailty Index predicts 30-day or hospital mortality in humans (critical limb ischemia after infrapopliteal revascularization) (HR 6.32, 95% CI 1.43–43.7).

    “Only the CLI Frailty Index was found to be a risk factor for morbidity (HR, 3.21; 95% CI, 1.45-7.27; P = .004) and 30-day or hospital mortality”

    Humanscritical limb ischemia after infrapopliteal revascularization30 days or hospitalizationn = 266

    Influence of frailty on treatment outcomes after revascularization in patients with critical limb ischemia

    Journal of vascular surgery

Morbidity

upin humans1HR 3.21

1 study
  1. CLI Frailty Index predicts morbidity in humans (critical limb ischemia after infrapopliteal revascularization) (HR 3.21, 95% CI 1.45–7.27).

    “Only the CLI Frailty Index was found to be a risk factor for morbidity (HR, 3.21; 95% CI, 1.45-7.27; P = .004)”

    Humanscritical limb ischemia after infrapopliteal revascularizationn = 266

    Influence of frailty on treatment outcomes after revascularization in patients with critical limb ischemia

    Journal of vascular surgery

Amputation-free survival

downin humans1HR 2.77

1 study
  1. CLI Frailty Index predicts amputation-free survival in humans (HR 2.77, 95% CI 1.78–4.32).

    “The CLI Frailty Index is a risk factor for 2-year AFS in CLI patients after revascularization.”

    Humanscritical limb ischemia after infrapopliteal revascularization; hazard ratio for the adverse endpoint2 yearsn = 266

    Influence of frailty on treatment outcomes after revascularization in patients with critical limb ischemia

    Journal of vascular surgery

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