Circulating fatty acid synthase
Biomarker1 paper5 findings
- Humans1
Effects
1Major adverse limb event risk discrimination
upin humans1
1 study
Major adverse limb event risk discrimination
upin humans1
Circulating fatty acid synthase improves major adverse limb event risk discrimination in humans (C-statistic from 0.649 to 0.764).
HumansAdding cFAS to standard clinical covariates in patients undergoing elective vascular surgery1 yearn = 657
Blood enzyme and frailty score help predict vascular surgery risks · medRxiv : the preprint server for health sciences · 12 Aug 2026 · Preprint
Associations
4Reintervention
upin humans1HR 2.5
1 study
Reintervention
upin humans1HR 2.5
Circulating fatty acid synthase is associated with reintervention in humans (Adjusted HR 2.50, 95% CI 1.37–4.57).
HumansHigh serum cFAS in patients undergoing elective vascular surgery5 yearsn = 657
Blood enzyme and frailty score help predict vascular surgery risks · medRxiv : the preprint server for health sciences · 12 Aug 2026 · Preprint
Major adverse limb events
upin humans1HR 4.53
1 study
Major adverse limb events
upin humans1HR 4.53
Circulating fatty acid synthase is associated with major adverse limb events in humans (Adjusted HR 4.53, 95% CI 2.04–10.05).
HumansHigh serum cFAS in patients undergoing elective vascular surgery5 yearsn = 657
Blood enzyme and frailty score help predict vascular surgery risks · medRxiv : the preprint server for health sciences · 12 Aug 2026 · Preprint
Mortality
upin humans1HR 1.77
1 study
Mortality
upin humans1HR 1.77
Circulating fatty acid synthase is associated with mortality in humans (Adjusted HR 1.77, 95% CI 1.05–3.00).
HumansHigh serum cFAS in patients undergoing elective vascular surgery5 yearsn = 657
Blood enzyme and frailty score help predict vascular surgery risks · medRxiv : the preprint server for health sciences · 12 Aug 2026 · Preprint
Major adverse events
upin humans1HR 1.94
1 study
Major adverse events
upin humans1HR 1.94
Circulating fatty acid synthase is associated with major adverse events in humans (Adjusted HR 1.94, 95% CI 1.31–2.85).
HumansHigh serum cFAS in patients undergoing elective vascular surgery5 yearsn = 657
Blood enzyme and frailty score help predict vascular surgery risks · medRxiv : the preprint server for health sciences · 12 Aug 2026 · Preprint
Latest
1Blood enzyme and frailty score help predict vascular surgery risks
An observational study of 657 patients found that combining the two measures improved risk prediction beyond standard clinical factors.An observational study of 657 patients found that combining the two measures improved risk prediction beyond standard clinical factors.