Chromosomal amplifications
1 paper studies it3 more mention it1 finding
- Humans1
Associations
1Pathogen exposure
upin humans1
1 study
Pathogen exposure
upin humans1
Pathogen exposure is associated with chromosomal amplifications in humans (occurred at 30 years old on average).
“In tumors from patients exposed to O. viverrini we find that the earliest chromosomal amplifications carrying driver genes occurred at 30 years old on average”
Humanstumors from patients exposed to O. viverrini
Natural history of a parasite–induced biliary cancer
medRxivPreprint
Latest
1 paper in 12 monthsPLOS Biology
Chromosome duplication causes premature aging via defects in ribosome quality control
Experiments in yeastMechanisms
medRxiv
Natural history of a parasite–induced biliary cancer
Preprint: cohort study of 11,517 peoplePopulations
bioRxiv
Premature aging in aneuploid yeast is caused in part by aneuploidy-induced defects in Ribosome Quality Control
Preprint: experiments in yeastMechanisms
Nucleic Acids Research
Replicative aging is associated with loss of genetic heterogeneity from extrachromosomal circular DNA in Saccharomyces cerevisiae
Experiments in cellsMechanisms