iScience
Silencing neurons changes support and immune cells in mice
Experiments in adult and middle-aged mice found region-specific changes in brain support and immune cells after researchers blocked communication from selected nerve…Experiments in adult and middle-aged mice found region-specific changes in brain support and immune cells after researchers blocked communication from selected nerve cells.
Mouse studyMechanisms
Who was studiedAdult and middle-aged mice, against control mice
What changedSilenced cortical regions had stronger support-cell reactions and higher immune-cell density than controls
The catchNerve-cell projections also degenerated, complicating attribution of glial changes to silencing alone