Cell-type differentiation of CpG methylation
1 finding
Associations
1Age-associated DNA methylation alterations
upin humans1
1 study
Age-associated DNA methylation alterations
upin humans1
Cell-type differentiation of CpG methylation is associated with age-associated DNA methylation alterations in humans.
“We reveal that CpGs that are highly differentiated between cell types are especially prone to age-associated DNA methylation alterations”
Humansbrain neurons and non-neuronal cells, primarily oligodendrocytes
Human Brain Aging is Associated with Dysregulation of Cell-Type Epigenetic Identity
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