Cell-based polygenic risk scores
Biomarker1 paper3 findings
- Humans1
Associations
3Complement C4a protein expression
upin humans1
1 study
Complement C4a protein expression
upin humans1
Cell-based polygenic risk scores are associated with complement C4a protein expression in humans.
Humanshigh genetic risk statuspostmortem brain
Genetic risk scores linked to faster progression to Alzheimer’s · Alzheimer's & dementia : the journal of the Alzheimer's Association · 1 Oct 2026
Temporal lobe atrophy, glucose metabolism, and global amyloid burden
mixedin humans1
1 study
Temporal lobe atrophy, glucose metabolism, and global amyloid burden
mixedin humans1
Cell-based polygenic risk scores are associated with temporal lobe atrophy, glucose metabolism, and global amyloid burden in humans.
Humansbrain
Genetic risk scores linked to faster progression to Alzheimer’s · Alzheimer's & dementia : the journal of the Alzheimer's Association · 1 Oct 2026
Progression to Alzheimer's disease
upin humans1
1 study
Progression to Alzheimer's disease
upin humans1
Cell-based polygenic risk scores predict progression to Alzheimer's disease in humans (Hazard ratios: 1.25–2.02).
HumansAPOE-concentrated and APOE-independent genetic risk axes
Genetic risk scores linked to faster progression to Alzheimer’s · Alzheimer's & dementia : the journal of the Alzheimer's Association · 1 Oct 2026
Latest
1Genetic risk scores linked to faster progression to Alzheimer’s
In two observational cohorts, genetic scores were linked to faster progression to Alzheimer’s disease, with hazard ratios, a measure of risk over…In two observational cohorts, genetic scores were linked to faster progression to Alzheimer’s disease, with hazard ratios, a measure of risk over time, of 1.25 to 2.02.