Cardiac chamber volumetry

1. Cardiac chamber volumetry raises the risk of heart failure in humans (p < 0.001).

   “Higher chamber volumes of the left atrium (LA), left ventricle (LV), right atrium (RA), and LV myocardium were significantly associated with increased risk for incident HF at each follow-up interval (p-value < 0.001).”

   Humansasymptomatic patients without known cardiac diseasen = 2,966

   AI-Based Cardiac Chamber Volumetry from CAC CT Enhances Heart Failure Prediction Beyond PREVENT-HF

   AHA Scientific Sessions 2025 abstract·3 Nov 2025

2. Cardiac chamber volumetry predicts heart failure in humans (3yr AUC 0.765 vs 0.629, p=0.002).

   “Time dependent AUC of all chamber volumes alone outperformed PREVENT-HF [3yr: 0.765 vs. 0.629 (p=0.002), 5yr: 0.764 vs 0.673 (p=0.047), 10yr: 0.737 vs. 0.775 (p=0.430)].”

   Humansasymptomatic patients without known cardiac diseasen = 2,966

   AI-Based Cardiac Chamber Volumetry from CAC CT Enhances Heart Failure Prediction Beyond PREVENT-HF

   AHA Scientific Sessions 2025 abstract·3 Nov 2025

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