Candidate senescence biomarkers

1. Idiopathic pulmonary fibrosis increases candidate senescence biomarkers in humans.

   “The circulating levels of several senescence biomarkers were significantly elevated in persons affected by IPF compared to controls.”

   HumansIPF vs controls

   Biomarkers of cellular senescence in idiopathic pulmonary fibrosis

   Respiratory research·Apr 7, 2023

More on Idiopathic pulmonary fibrosis

1. Candidate senescence biomarkers are associated with CDKN2A in humans.

   “plasma concentrations of several biomarkers were associated with their expression levels in lung tissue as well as the expression of P16.”

   Humanslung tissue

   Biomarkers of cellular senescence in idiopathic pulmonary fibrosis

   Respiratory research·Apr 7, 2023

More on CDKN2A

1. Candidate senescence biomarkers are associated with mortality in humans.

   “senescence biomarkers were also associated with mortality in IPF participants.”

   Humansin IPF participants

   Biomarkers of cellular senescence in idiopathic pulmonary fibrosis

   Respiratory research·Apr 7, 2023

1. Candidate senescence biomarkers are associated with pulmonary function in humans.

   “A subset of biomarkers accurately classified participants as having or not having the disease and was significantly correlated with measures of pulmonary function”

   Humansin IPF participants

   Biomarkers of cellular senescence in idiopathic pulmonary fibrosis

   Respiratory research·Apr 7, 2023