1 paper2 findings
Coronary heart disease risk reclassification
upin humans1
CAC volume and density score improves coronary heart disease risk reclassification in humans (Continuous net reclassification improvement 0.54 (95% CI 0.43–0.64) versus 0.45 (95% CI 0.34–0.56) for Agatston score).
“resulted in greater continuous net reclassification improvement (0.54 [95% CI, 0.43-0.64]) compared with the Agatston score (0.45 [95% CI, 0.34-0.56])”
HumansMESA participants with CAC>0; added to pooled cohort equationsn = 3,360
Revised artery calcium score better predicts heart disease
Circulation. Cardiovascular imaging12 Oct 2026
Coronary heart disease risk discrimination
upin humans1
CAC volume and density score improves coronary heart disease risk discrimination in humans (C-index 0.699 (95% CI 0.675–0.723) versus 0.687 (95% CI 0.663–0.711)).
“significantly improves risk discrimination and reclassification compared with the Agatston score.”
HumansMESA participants with CAC>0; added to pooled cohort equations and compared with the Agatston scoren = 3,360
Revised artery calcium score better predicts heart disease
Circulation. Cardiovascular imaging12 Oct 2026
A measure of how well models ranked heart disease risk was 0.699 with the revised score versus 0.687 with the usual calcium score.A measure of how well models ranked heart disease risk was 0.699 with the revised score versus 0.687 with the usual calcium score.