2 papers6 findings
Heritability
upin silico1
Brain-predicted age is associated with heritability in silico (h2 ≥ 0.5).
“Brain-predicted age was a heritable phenotype for all models and input data (h2 ≥ 0.5).”
In silicohealthy
NeuroImage29 Jul 2017
Chronological age
upin silico1
Brain-predicted age predicts chronological age in silico (r = 0.96, MAE = 4.16 years).
“CNN accurately predicted chronological age using GM (correlation between brain-predicted age and chronological age r = 0.96, mean absolute error [MAE] = 4.16 years)”
In silicobrain
NeuroImage29 Jul 2017
Fluid intelligence
downin humans1
Brain-predicted age is associated with fluid intelligence in humans.
“Having a brain-predicted age indicative of an older-appearing brain was associated with: weaker grip strength, poorer lung function, slower walking speed, lower fluid intelligence, higher allostatic load and increased mortality risk.”
Humans
Molecular psychiatry25 Apr 2017
Walking speed
downin humans1
Brain-predicted age is associated with walking speed in humans.
“Having a brain-predicted age indicative of an older-appearing brain was associated with: weaker grip strength, poorer lung function, slower walking speed, lower fluid intelligence, higher allostatic load and increased mortality risk.”
Humans
Molecular psychiatry25 Apr 2017
Grip strength
downin humans1
Brain-predicted age is associated with grip strength in humans.
“Having a brain-predicted age indicative of an older-appearing brain was associated with: weaker grip strength, poorer lung function, slower walking speed, lower fluid intelligence, higher allostatic load and increased mortality risk.”
Humans
Molecular psychiatry25 Apr 2017
Mortality
upin humans1
Brain-predicted age predicts mortality in humans.
“Having a brain-predicted age indicative of an older-appearing brain was associated with: weaker grip strength, poorer lung function, slower walking speed, lower fluid intelligence, higher allostatic load and increased mortality risk.”
Humans
Molecular psychiatry25 Apr 2017
The gap between scan-estimated and actual age exceeded age-matched controls by 7.64 years in schizophrenia and 7.61 years in frontotemporal dementia.The gap between scan-estimated and actual age exceeded age-matched controls by 7.64 years in schizophrenia and 7.61 years in frontotemporal dementia.