Experimental Biology and Medicine
Genetic analysis links hip and thigh fat to lower liver cancer odds
In FinnGen, genetically predicted hip and thigh fat, adjusted for body size, was associated with lower liver cancer odds, with an odds ratio of 0.444.In FinnGen, genetically predicted hip and thigh fat, adjusted for body size, was associated with lower liver cancer odds, with an odds ratio of 0.444.
Mendelian randomizationMechanisms
Who was studiedIndividuals of European ancestry
What changedGenetically predicted gluteofemoral adipose tissue was associated with lower hepatocellular carcinoma risk (OR = 0.444)
The catchOnly 500 hepatocellular carcinoma cases were analyzed in the discovery dataset