Bias-corrected predicted age deviation

Biomarker

1 paper3 findings

  • In silico1

Associations

3

Mortality

upin humans1

1 study
  1. Bias-corrected predicted age deviation is associated with mortality in humans (1.4% per 1-year increase).

    “Multivariate Cox showed each 1-year increase in both PAD and PADbc was associated with a 1.4% increased mortality hazard.”

    Humans

    Artificial intelligence-predicted ECG age gap as a biomarker: bias-adjusted correlation with mortality and cardiovascular risk factors

    European heart journal. Digital health28 Nov 2025

Lifespan

downin humans1

1 study
  1. Bias-corrected predicted age deviation is associated with lifespan in humans.

    “Kaplan-Meier revealed that PADbc above its MAE was linked to lower survival, whereas PAD showed the opposite.”

    HumansPADbc above its MAE

    Artificial intelligence-predicted ECG age gap as a biomarker: bias-adjusted correlation with mortality and cardiovascular risk factors

    European heart journal. Digital health28 Nov 2025

Cardiovascular risk factors

upin humans1

1 study
  1. Bias-corrected predicted age deviation is associated with cardiovascular risk factors in humans.

    “higher PADbc (r = 0.00) was associated with higher prevalence of risk factors.”

    Humans

    Artificial intelligence-predicted ECG age gap as a biomarker: bias-adjusted correlation with mortality and cardiovascular risk factors

    European heart journal. Digital health28 Nov 2025

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