BBB water exchange rate

Biomarker

2 papers2 findings

  • Humans2

Associations

2

Male sex

downin humans1

1 study
  1. Male sex is associated with BBB water exchange rate in humans.

    “a remarkable decline in BBB kw beginning in the early 60s, which was more pronounced in males.”

    Humansage-related decline in cognitively normal participantsbrainmales compared with femaless

    Age-Related Decline in BBB Function is More Pronounced in Males than Females

    eLifeApr 15, 2024Preprint

Older age

downin humans1

1 study
  1. Older age is associated with BBB water exchange rate in humans.

    “We found that the pattern of BBB kw decline with aging varies across brain regions.”

    Humanscognitively normal participantsbrainn = 186

    Age-Related Decline in BBB Function is More Pronounced in Males than Females

    eLifeApr 15, 2024Preprint

Funding

1 grant since 2024

National Institute of Neurological Disorders and StrokeUS$1.4m

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