Baseline global white matter hyperintensity volume

Biomarker1 paper1 finding

  • Human trial1

Associations

1

Neuropsychiatric symptom reduction

downin humans1

1 study
  1. Baseline global white matter hyperintensity volume is associated with neuropsychiatric symptom reduction in humans (Interaction β = 0.258, SE = 0.080).

    Human trialvascular mild cognitive impairment; N-acetylcysteine plus exercise group; WMH × time × treatment interactionbrain white matterN-acetylcysteine 2400 mg daily6 months

    Brain scan findings linked to symptom relief in memory trial · Journal of Alzheimer's disease : JAD · 7 Oct 2026

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Journal of Alzheimer's DiseaseHuman trial

Brain scan findings linked to symptom relief in memory trial

In a six-month trial of 51 people with vascular mild cognitive impairment, lower volumes of bright brain areas were linked to greater symptom…In a six-month trial of 51 people with vascular mild cognitive impairment, lower volumes of bright brain areas were linked to greater symptom reductions.