Arginine metabolism

1 paper studies it18 more mention it

Humans1

Funding

1 grant since 2020

National Institute on AgingUS$329.8k

Are the impairments of arginine metabolism as found in Alzheimer's disease also present in patients developing post-operative delirium and cognitive decline?
National Institute on AgingWilliam Beaumont Hospital Research InstUS$329.8k2020–2023

Latest

2 papers in 12 months

CureusSep 13

Dimethylarginine Dimethylaminohydrolase 1 (DDAH1)-Arginine Metabolic Axis Is Independently Associated With Alzheimer's Disease Risk in the UK Biobank

Cohort study of 50,988 peopleAmino acid metabolism

PLOS PathogensJul 6

Staphylococcus aureus rewires arginine metabolism to drive mammary aging via macrophage-epithelial crosstalk

Experiments in miceAmino acid metabolism

Discovery ImmunologyMay 15

Spermidine suppresses DC activation via eIF5A hypusination and metabolic adaptation

Experiments in cellsOxidative phosphorylation

Aging CellOct 31

Arginine metabolism is a biomarker of red blood cell and human aging

Cohort study of 13,757 peopleAmino acid metabolism

Cell MetabolismOct 17

Lighting up arginine metabolism reveals its functional diversity in physiology and pathology

Study in peopleAmino acid metabolism

Aging CellJan 18

L-arginine metabolism ameliorates age-related cognitive impairment by Amuc_1100-mediated gut homeostasis maintaining

Experiments in miceCognitive impairment

Communications BiologyJun 28

Spermidine from arginine metabolism activates Nrf2 and inhibits kidney fibrosis

Experiments in miceSpermidine

Redox BiologyNov 11

Impairments of intestinal arginine and NO metabolisms trigger aging-associated intestinal barrier dysfunction and 'inflammaging'

Experiments in miceAmino acid metabolism

Neurochemistry InternationalJul 28

Altered brain arginine metabolism with age in the APPswe/PSEN1dE9 mouse model of Alzheimer's disease

Experiments in animalsMechanisms

PharmacologyMay 27

Inhibition of p38mapk Reduces Adipose Tissue Inflammation in Aging Mediated by Arginase-II

Experiments in animalsMechanisms