Annulus-to-leaflet area

There is 1 paper on annulus-to-leaflet area in aging research: 1 observational study in people.

Biomarker

1 paper studies it3 findings

1 new paper in 30 daysSee all 1 papers on annulus-to-leaflet area

“Smaller annulus-to-leaflet area was associated with both prevalent (OR /1-SD decrease = 2.46; 95% CI 1.60–3.78)”
Mitral Annulus-to-Leaflet Area: A Novel Quantitative Endophenotype for Mitral Valve Prolapse Enables Risk Stratification and Genetic DiscoveryAHA Scientific Sessions 2026 abstract2026doi:10.1161/circ.154.suppl_1.10873
  • Humans1

Associations

3

Mitral valve prolapse

downin humans1

1 study
  1. Annulus-to-leaflet area is associated with mitral valve prolapse in humans (genetic correlation) (Genetic correlation −0.44).

    “The annulus-to-leaflet area demonstrated significant genetic correlation with MVP”

    Humansgenetic correlation

    Mitral Annulus-to-Leaflet Area: A Novel Quantitative Endophenotype for Mitral Valve Prolapse Enables Risk Stratification and Genetic Discovery

    AHA Scientific Sessions 2026 abstract

More on Mitral valve prolapse

Incident mitral valve prolapse

upin humans1HR 3.16

1 study
  1. Annulus-to-leaflet area is associated with incident mitral valve prolapse in humans (per 1-SD decrease in annulus-to-leaflet area) (HR 3.16 per 1-SD decrease; 95% CI 2.27–4.41).

    “incident (HR /1-SD decrease = 3.16; 95% CI 2.27–4.41) MVP independent of measures of cardiac structure and function.”

    Humansper 1-SD decrease in annulus-to-leaflet areamitral valve

    Mitral Annulus-to-Leaflet Area: A Novel Quantitative Endophenotype for Mitral Valve Prolapse Enables Risk Stratification and Genetic Discovery

    AHA Scientific Sessions 2026 abstract

More on Incident mitral valve prolapse

Prevalent mitral valve prolapse

upin humans1OR 2.46

1 study
  1. Annulus-to-leaflet area is associated with prevalent mitral valve prolapse in humans (per 1-SD decrease in annulus-to-leaflet area) (OR 2.46 per 1-SD decrease; 95% CI 1.60–3.78).

    “Smaller annulus-to-leaflet area was associated with both prevalent (OR /1-SD decrease = 2.46; 95% CI 1.60–3.78)”

    Humansper 1-SD decrease in annulus-to-leaflet areamitral valve

    Mitral Annulus-to-Leaflet Area: A Novel Quantitative Endophenotype for Mitral Valve Prolapse Enables Risk Stratification and Genetic Discovery

    AHA Scientific Sessions 2026 abstract

More on Prevalent mitral valve prolapse

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