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AI-HFpEF diagnostic positivity

There is 1 paper on AI-HFpEF diagnostic positivity in aging research: 1 observational study in people. The newest story, Nov 1, 2026: “Ultrasound AI identified early heart failure in adults”.

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“an AI-HFpEF diagnostic positive result was associated with >2-fold higher incident HFpEF risk (aHR: 2.08; P < 0.001).”
Evaluation of an Echocardiography-Based Artificial Intelligence Algorithm for Early HFpEF Detection: A HeartShare/AMP-HF Cohort StudyJACC. Heart failure2026doi:10.1016/j.jchf.2026.103420
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Incident clinical heart failure with preserved ejection fraction

upin humans1

1 study

  1. AI-HFpEF diagnostic positivity predicts incident clinical heart failure with preserved ejection fraction in humans (UTSW cohort with structurally normal echocardiograms and no prior heart failure) (aHR 2.08; P < 0.001).

    “an AI-HFpEF diagnostic positive result was associated with >2-fold higher incident HFpEF risk (aHR: 2.08; P < 0.001).”

    HumansUTSW cohort with structurally normal echocardiograms and no prior heart failuremedian follow-up of 33 monthsn = 6,876

    Ultrasound AI identified early heart failure in adults

    JACC. Heart failure

More on Incident clinical heart failure with preserved ejection fraction

Early heart failure with preserved ejection fraction

upin humans1OR 3.26

1 study

  1. AI-HFpEF diagnostic positivity is associated with early heart failure with preserved ejection fraction in humans (MESA community cohort without clinically diagnosed heart failure) (OR 3.26; P < 0.001).

    “AI-HFpEF diagnostic positivity was associated with higher odds of early HFpEF (OR: 3.26; P < 0.001)”

    HumansMESA community cohort without clinically diagnosed heart failuren = 2,544

    Ultrasound AI identified early heart failure in adults

    JACC. Heart failure

More on Early heart failure with preserved ejection fraction

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JACC Heart Failure

Ultrasound AI identified early heart failure in adults

For distinguishing early disease, the AI scored 0.77 versus 0.70 for a clinical score in 2,544 adults without diagnosed heart failure.For distinguishing early disease, the AI scored 0.77 versus 0.70 for a clinical score in 2,544 adults without diagnosed heart failure.

Cohort · 2,544 peopleBiomarkers
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