Aging Discordance Index

Biomarker1 paper2 findings

  • Humans1

Associations

1

Cognitive function

downin humans1

1 study
  1. Aging Discordance Index predicts cognitive function in humans (β = -0.326, 95% CI: -0.575 to -0.077).

    HumansChinese older adults; adjusted for baseline cognition, sociodemographic, lifestyle, and clinical covariates3 yearsn = 1,688

    Uneven aging across body systems linked to cognitive decline · Journal of Alzheimer's disease : JAD · 8 Oct 2026

  2. Aging Discordance Index is associated with cognitive function in humans (β = -0.336, 95% CI: -0.598 to -0.075).

    HumansChinese older adults; fully adjusted analysis3 yearsn = 1,688

    Uneven aging across body systems linked to cognitive decline · Journal of Alzheimer's disease : JAD · 8 Oct 2026

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Journal of Alzheimer's DiseaseHumans

Uneven aging across body systems linked to cognitive decline

In 1,688 older adults in China, an index tracking uneven aging across five routine blood markers was associated with steeper cognitive decline over…In 1,688 older adults in China, an index tracking uneven aging across five routine blood markers was associated with steeper cognitive decline over three years.