1 paper5 findings
Intraindividual variability in processing speed
upin humans1
AgeDev increases intraindividual variability in processing speed in humans.
“Individuals with greater AgeDev showed more intraindividual variability in processing speed.”
Humansn = 139
Epigenetic age acceleration tracks lower baseline cognition and greater retest gains
The journals of gerontology. Series A, Biological sciences and medical sciencesSep 26, 2026
Cognitive change across time
no changein humans1
AgeDev has no effect on cognitive change across time in humans.
“Neither AgeDev nor chronological age predicted differences in cognitive change across time.”
Humansn = 139
Epigenetic age acceleration tracks lower baseline cognition and greater retest gains
The journals of gerontology. Series A, Biological sciences and medical sciencesSep 26, 2026
Retest-related gains
upin humans1
AgeDev increases retest-related gains in humans.
“individuals with greater AgeDev and faster DunedinPACE showed greater retest-related gains within and across bursts.”
Humansn = 139
Epigenetic age acceleration tracks lower baseline cognition and greater retest gains
The journals of gerontology. Series A, Biological sciences and medical sciencesSep 26, 2026
Peak cognitive performance
downin humans1
AgeDev decreases peak cognitive performance in humans.
“baseline peak performance was lower for individuals with greater AgeDev, DunedinPACE, and chronological age.”
Humansn = 139
Epigenetic age acceleration tracks lower baseline cognition and greater retest gains
The journals of gerontology. Series A, Biological sciences and medical sciencesSep 26, 2026
Mortality
upin dogs1
AgeDev predicts mortality in dogs (hazard ratio = 1.75 per 1 year of AgeDev, p = 3.7e - 06).
“Positive deviations of biological from chronological age (AgeDev) measured by this composite score significantly correlated with a decreased survival probability (hazard ratio = 1.75 per 1 year of AgeDev, p = 3.7e - 06).”
Animalsblood12 yearsn = 829
GeroScienceOct 1, 2024
In middle-aged adults, biological aging correlated with processing speed variability and baseline performance but did not predict cognitive change over time.In middle-aged adults, biological aging correlated with processing speed variability and baseline performance but did not predict cognitive change over time.