Age-associated white matter hyperintensity volume

Cardiorespiratory fitness is associated with age-associated white matter hyperintensity volume in humans.

“the positive regression slopes of FW and WMH volume with age were lower in those with higher V̇O2peak than those with lower V̇O2peak.”

Humansage × peak oxygen consumption interaction in healthy adultsbrain white mattern = 177

Associations of cardiorespiratory fitness with brain white matter microstructural integrity and white matter hyperintensity volume across the adult lifespan

GeroScience·29 Apr 2025