Henar Rodríguez Arias

RAS/MAPK overactivation drives motor axon loss in flies

An unbiased genetic screen in Drosophila revealed that excessive RAS/MAPK signaling causes adult-onset neurodegeneration that a MEK inhibitor rescues…An unbiased genetic screen in Drosophila revealed that excessive RAS/MAPK signaling causes adult-onset neurodegeneration that a MEK inhibitor rescues in a dose-dependent manner.