Ellen A. A. Nollen
University Medical Center Groningen2 papersORCID 0000-0003-3740-6373OpenAlex
Papers
bioRxivModel organismsPreprint
A PPAR-gamma counterpart protects worm neurons by coordinating lipids and mitochondria
Researchers show that SEX-1 regulates sphingolipid metabolism and mitochondrial quality control in Caenorhabditis elegans, but its protective activity…Researchers show that SEX-1 regulates sphingolipid metabolism and mitochondrial quality control in Caenorhabditis elegans, but its protective activity declines with age.
EMBO ReportsModel organisms
Alpha-synuclein impairs triglyceride metabolism and mitochondrial structure in aging nematodes
Restoring lipid balance through medium-chain triglycerides or fatty acid inhibition protected worms from alpha-synuclein-driven movement deficits.Restoring lipid balance through medium-chain triglycerides or fatty acid inhibition protected worms from alpha-synuclein-driven movement deficits.