Liying Xue

Vanderbilt University2 papersORCID 0009-0006-9281-4598OpenAlex

Papers

medRxivHumansPreprint

Clonal hematopoiesis is linked to frailty in human cohorts

An analysis of 730,088 participants across four cohorts found clonal hematopoiesis was strongly associated with incident frailty and faster functional…An analysis of 730,088 participants across four cohorts found clonal hematopoiesis was strongly associated with incident frailty and faster functional decline.

medRxivHumansPreprint

ASXL1-mutant clonal hematopoiesis links to aortic valve disease

In cohort data and cell models, ASXL1 mutations tracked with incident aortic stenosis and promoted valvular calcification that was reduced by IL-1 or…In cohort data and cell models, ASXL1 mutations tracked with incident aortic stenosis and promoted valvular calcification that was reduced by IL-1 or IL-6 inhibition.