Joel A. Hrit
Van Andel Institute1 paperORCID 0000-0002-4497-956XOpenAlex
Papers
bioRxivCellsPreprint
A UHRF1 feed-forward mechanism sustains DNA methylation at CpG-sparse genomic regions
Binding of mono-ubiquitinated histone H3 by UHRF1 drives multi-mono-ubiquitination to prevent methylation loss in regions typically degraded during…Binding of mono-ubiquitinated histone H3 by UHRF1 drives multi-mono-ubiquitination to prevent methylation loss in regions typically degraded during cancer and aging.