Trevor P. Fidler
University of California, San Francisco1 paperORCID 0000-0002-0758-9984OpenAlex
Papers
medRxivHumansPreprint
ASXL1-mutant clonal hematopoiesis links to aortic valve disease
In cohort data and cell models, ASXL1 mutations tracked with incident aortic stenosis and promoted valvular calcification that was reduced by IL-1 or…In cohort data and cell models, ASXL1 mutations tracked with incident aortic stenosis and promoted valvular calcification that was reduced by IL-1 or IL-6 inhibition.