Philippe Lefèbvre

AMPK lengthens the circadian clock period through NAD+-dependent regulation of Bmal1

Experiments in human cells and computational modeling show that fasting sensor AMPK requires NAD+ and PGC-1-alpha to modulate cellular circadian…Experiments in human cells and computational modeling show that fasting sensor AMPK requires NAD+ and PGC-1-alpha to modulate cellular circadian rhythms.