Wakako Kawarazaki
International University of Health and Welfare (IUHW)1 paperORCID 0000-0002-1332-8537
Papers
Acta PhysiologicaAnimals
Klotho deficiency disrupts potassium balance in mice
In Klotho-deficient mice, renal mTORC1 activation suppressed potassium channel ROMK1 to cause hyperkalemia, which rapamycin or Klotho supplementation…In Klotho-deficient mice, renal mTORC1 activation suppressed potassium channel ROMK1 to cause hyperkalemia, which rapamycin or Klotho supplementation reversed.