From ClinicalTrials.gov

Clinical trials

Trials of drugs and interventions aimed at aging, of age-related conditions through aging biology, and of healthspan itself: new registrations, status changes and first results.

Phase 2CompletedAge-related condition

Study to Determine Optimal Dose and Evaluate Safety, Tolerability, and Pharmacokinetics of Progerinin in Patients With Hutchinson-Gilford Progeria Syndrome (HGPS)

Progerinin, Lonafarnib in Hutchinson-Gilford Progeria Syndrome

PRG Science & Technology Co., Ltd. · 10 enrolled · NCT06775041 · updated 2 Oct 2026

ObservationalCompletedHealthspan endpoint

Registered · 2 Oct 2026

Biomarkers, Abdominal Muscle, and Frailty in CKD

total antioxidant status, total oxidant status, monocyte chemotactic protein-1 in Chronic Kidney Disease, Abdominal Muscles/Ultrasonography, Frailty

Ankara City Hospital Bilkent · 88 enrolled · NCT07854275 · updated 2 Oct 2026

CompletedAge-related condition

A Prolonged Nightly Fasting for Men on ADT for PCa

Prolonged Nightly Fasting (PNF+), Healthy Diet Text Messaging in Prostate Cancer

Thomas Jefferson University · 40 enrolled · NCT07462403 · updated 2 Oct 2026

CompletedAge-related condition

Peanut Sip Feeding Protocol

Peanut protein in Protein Metabolism

Texas A&M University · 13 enrolled · NCT06693544 · updated 1 Oct 2026

CompletedGeroscience intervention

Impact of Time-Restricted Eating on Metabolic Homeostasis, Inflammation and Oxidative Stress in Metabolic Syndrome (TREMNIOS)

Time-Restricted Eating in Metabolic Syndrome, Overweight or Obesity, PreDiabetes

Nicolaus Copernicus University · 27 enrolled · NCT04328233 · updated 1 Oct 2026