No phaseCompleted
Effects of Short-Term Creatine Supplementation on Cognitive Function in Healthy Young Adults
The Effects of Short-Term, High-Dosage Creatine Supplementation on Cognitive Measures Following Mental Fatigue in Healthy Young Adults
- Sponsor
- University of Northern Iowa (Academic or other)
- Enrolment
- 24 enrolled
- Conditions
- Cognitive Function Assessment; Mental Fatigue
- Interventions
- Creatine Monohydrate; Maltodextrin Placebo
- Ages
- adults, older adults
- Registry
- NCT07867041
Full record on ClinicalTrials.gov
From the registry
This study examined whether short-term creatine supplementation affects cognitive function in healthy young adults. Participants were randomly assigned to take either creatine monohydrate or a placebo for 10 days. Participants took 30 grams per day, divided into six 5-gram doses. Before and after the supplementation period, participants completed cognitive tests designed to assess areas such as memory, attention, reaction time, and processing speed. Participants also completed a 30-minute mentally challenging Stroop task, and brain oxygenation was measured during cognitive testing using functional near-infrared spectroscopy (fNIRS). The purpose of the study was to determine whether 10 days of high-dose creatine supplementation improves cognitive performance compared with placebo following a mentally challenging task.
Primary outcomes
- Cognitive Performance Standard Scores Assessed by Central Nervous System Vital Signs (CNSVS)
- Stroop Task Performance - Reaction Time
- Stroop Test Performance - Accuracy
History
Registered
Primary completion
Started