No phaseRecruiting

Assessing the Potential Role of the Gut Microbiome in Modulating Physical Abilities in Humans

Sponsor
Assaf-Harofeh Medical Center (Government)
Enrolment
70 planned
Conditions
Physical Abilities; FMT
Interventions
Antibiotics; Autologous Fecal Microbiota Transplantation; Cellules Pills; placebo capsules
Ages
adults
Registry
NCT05024188

Full record on ClinicalTrials.gov

From the registry

The intestinal microbiome is a microbial system that is influenced by host genetics and environmental exposures such as nutrition, stress and medications. There is a growing body of evidence indicating the significant contribution of the gut microbiome to host health and disease. Furthermore, it has been shown that exercise may modify the microbiome composition. However, important mechanistic questions related to the possible associations between exercise and the human gut microbiome remain unanswered. In this study, the investigators are using advanced state-of-the-art measurements of physical activity level and related metabolic parameters whether there is a connection between the microbiome and physical abilities in healthy participants and whether antibiotics consumption can influence host physical abilities and glycemic responses through changes induced in microbiome composition and function.

Primary outcomes

  • Microbiome Profiling
  • Physical ability

History

  1. Study completion expected

  2. Primary completion expected

  3. Last registry update

  4. Started

  5. Registered