Papers by Yun Li

20 results

  1. HGG Advances

    Summary-level genetic method improves Alzheimer's risk prediction

    The endoPRS-SS framework boosted computational efficiency up to 90-fold while using summary statistics and multiple endophenotypes to improve Alzheimer's disease risk…The endoPRS-SS framework boosted computational efficiency up to 90-fold while using summary statistics and multiple endophenotypes to improve Alzheimer's disease risk prediction.

    Computational studyAlzheimer's disease
  2. Communications Biology

    East Asian GWAS reveals shared and distinct diabetes pathways

    In nearly 600,000 individuals, multi-ancestry fine-mapping resolved 521 causal signals for type 2 diabetes, with 74% shared between East Asian and European ancestries.In nearly 600,000 individuals, multi-ancestry fine-mapping resolved 521 causal signals for type 2 diabetes, with 74% shared between East Asian and European ancestries.

    Genetic association study of 596,778 peopleType 2 diabetes
  1. JAMA Neurology

    Hearing aids did not cut dementia conversion in older adults

    Over 24 months, dementia conversion was 3.09% with hearing aids compared with 4.74% with hearing care education, a non-significant difference.Over 24 months, dementia conversion was 3.09% with hearing aids compared with 4.74% with hearing care education, a non-significant difference.

    Randomised trial in 703 peopleDementia