73 results
Average body weight fell between 13.6% and 19.7% across drug doses compared with 2.0% on placebo over 24 weeks.Average body weight fell between 13.6% and 19.7% across drug doses compared with 2.0% on placebo over 24 weeks.
Pairing 390 nm irradiation with beta-galactosidase cleavage improved prodrug selectivity in senescence models and increased death in senescent lung cancer patient-derived…Pairing 390 nm irradiation with beta-galactosidase cleavage improved prodrug selectivity in senescence models and increased death in senescent lung cancer patient-derived organoids.
Across eight external cohorts, the score yielded C-indices of 0.67 to 0.86, outperforming recalibrated conventional comorbidity indices by absolute gains of 0.12 to 0.21.Across eight external cohorts, the score yielded C-indices of 0.67 to 0.86, outperforming recalibrated conventional comorbidity indices by absolute gains of 0.12 to 0.21.
Computational screening identified the natural compound, which interacts with CHK1 to blunt replication stress and fibrotic signaling.Computational screening identified the natural compound, which interacts with CHK1 to blunt replication stress and fibrotic signaling.
The highest quartile of moderate activity was tied to a hazard ratio of 0.41 compared with the lowest quartile in 47,861 hypertensive adults.The highest quartile of moderate activity was tied to a hazard ratio of 0.41 compared with the lowest quartile in 47,861 hypertensive adults.