Papers by R. Li

122 results

  1. Functional & Integrative Genomics

    Blood taurine linked to common and rare DNA variants

    An analysis of 36,490 European individuals identified six regions with common DNA variants and two with rare variants associated with blood taurine levels.An analysis of 36,490 European individuals identified six regions with common DNA variants and two with rare variants associated with blood taurine levels.

    Study of 36,490 peopleMechanisms
  2. Research Square

    Exercise benefits on late-life depression differ across nations

    A preprint finds physical activity protected against depressive symptoms in US older adults (β = −2.734), but effects varied by education and living arrangements across…A preprint finds physical activity protected against depressive symptoms in US older adults (β = −2.734), but effects varied by education and living arrangements across countries.

    Preprint: cohort study in peopleDepression
  3. Ophthalmology

    Genetically proxied CETP inhibition links to higher AMD risk

    In drug-target Mendelian randomization, proxied CETP inhibition was associated with advanced AMD in Europeans (OR 1.45) and exudative AMD in East Asians (OR 3.14).In drug-target Mendelian randomization, proxied CETP inhibition was associated with advanced AMD in Europeans (OR 1.45) and exudative AMD in East Asians (OR 3.14).

    Mendelian randomisation in 457,242 peopleCETP
  4. Nature Communications

    Microglial ALKBH5 loss protects fat browning in aging male mice

    Knocking out the RNA demethylase ALKBH5 in microglia enhanced sympathetic innervation and preserved subcutaneous brown adipocytes in aging male mice.Knocking out the RNA demethylase ALKBH5 in microglia enhanced sympathetic innervation and preserved subcutaneous brown adipocytes in aging male mice.

    Experiments in miceMechanisms